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» Współczesne poglądy na temat etiopatogenezy i leczenia szczeliny odbytu

© Borgis - Nowa Medycyna 3, p. 169-172
*Agnieszka Kucharczyk1, Przemysław Ciesielski2, Małgorzata Kołodziejczak1
Współczesne poglądy na temat etiopatogenezy i leczenia szczeliny odbytu
current views on etiopathogenesis and treatment of anal fissures
1Oddział Chirurgii Ogólnej z Pododdziałem Proktologii Szpitala na Solcu w Warszawie
Orydynator: dr n. med. Jacek Bierca
Kierownik Proktologii: dr hab. n. med. Małgorzata Kołodziejczak
2Oddział Chirurgii Ogólnej, Szpital Powiatowy w Wołominie
Orydynator: dr n. med. Krzysztof Górnicki
Key words:
1. Bielecki K: Szczelina odbytu-problem proktologiczny. [W:] Proktologia. Red. Bielecki K, Dziki A, 2000; 8: 1501-156. 2. Gathright B: Anal fissure and stenosis. Materiały naukowe I Międzynarodowego Sympozjum Proktologicznego, 1999; 18-21. 3. Trzciński R, Dziki A: Szczeliny odbytu – objawy, etiologia i leczenie. Proktologia 2001; vol. 2: 337-349. 4. Bielecki K: Szczelina odbytu. Postępy Nauk Medycznych, 2006; t. XIX, nr 5: 198-203. 5. Gathright B: Probably more than you ever wanted to know about anal fissure. Materiały naukowe III Miedzynarodowego Sympozjum Proktologicznego, 1999; 133-141. 6. Oh Ch et al.: Anal fissure. Dis Colon Rectum 1995; 38: 378-382. 7. Schouten WR et al.: Ischemic nature of anal fissure. Br J Surg 1996; 83: 63-65. 8. Schouten WR, Briel JW, Auwerda JJA: Relationship between anal pressure and anodermal blood flow. The vascular pathogenesis of anal fissures. Dis Colon Rectum 1994; 37: 664. 9. Lund JN: Nitric oxide deficiency in the internal anal sphincter of patients with chronic anal fissure. Int J Colorectal Dis 2006; 21(7): 673-5. 10. Maria G et al.: Identification of anti-endothelial cell antibodies in patients with chronic anal fissure. Surgery 1999; 126: 535-539. 11. Gorfine SR: Treatment of benign anal disease with topical nitroglycerin. Dis Colon Rectum 1995; 38 (5): 453-456. 12. Bielecki K, Kołodziejczak M: A prospective randomized trial of diltiazem and glyceryltrinitrate ointment In the treatment of chronic fissure. Colorectal Dis 2003; 5: 256-257. 13. Carapeti EA, et al.: Randomized controlled trial shows that glyceryl trinitrate heals anal fissures, higher doses are not more effective, and there is a high recurrence rate. Gut 1999; 44: 727-730. 14. Loder PB et al.: Reversible chemical sphincterotomy by local application of glyceryl trinitrate. Br J Surg 1994; 81: 1386-1389. 15. Lund JN, Scholefield JH: A randomized, prospective, double-blind, placebo-controlled trial of glyceryl trinitrate ointment in treatment of anal fissure. Lancet 1997; 349: 11-14. 16. Schouten WR et al.: Pathophysiological aspects and clinical outcome of intra-anal application of isosorbide dinitrate in patients with chronic anal fissure. Gut 1996; 39: 465-469. 17. Antropoli C et al.: Nifedipine for local use in conservative treatment of anal fissure. Dis Colon Rectum 1999; 42, 8: 1011-1015. 18. Jonas M, Speake W, Scholefield JH: Diltiazem heals glyceryl trinitrate-resistant chronic anal fissure: prospective study. Dis Colon Rectum 2002; 45: 1091-1095 19. Narayanan S et al.: Changing trends in the management of chronic anal fissure. Brit J Surg 2005; 92, suppl. 1 abstrakt 7483. 20. Medei B: Recent Advances in pharmacotherapy of chronic anal fissure: an update Asian J Surg 2008; 31 (3): 154-63. 21. Hallan RI et al.: Treatment of anismus in intractable constipation with botulinum A toxin. Lancet 1988; 24: 714-717. 22. Jost WH, Schimrigk K: Therapy of anal fissure using botulin toxin. Dis Colon Rectum 1994; 37: 1321-1324. 23. Jost WH, Schimrigk K: Botulinum toxin in therapy of anal fissure. Lancet 1995; 345: 188-189. 24. Jost WH: One hundred cases of anal fissure treated with botulinum toxin early and long-term results. Dis Colon Rectum 1997; 40: 1029-1232. 25. Maria G et al.: Botulinum toxin injections in the internal anal sphincter for the treatment of chronic anal fissure. Ann Surg 1998; 228, 5: 664-669. 26. Minguez M et al.: Therapeutic effects of different doses of botulinum toxin In chronic anal fissure. Dis Colon Rectum 1999; 42, 8: 1016-1021. 27. Jonas-Obichere M et al.: Comparison of the effects of nitric oxide donors and calcium channel blockers on the intrinsic myogenic tone of sheep isolated internal anal sphincter. Brit J Surg 2005; 92: 1263-1269. 28. Sohn N et al.: Precise anorectal sphincter dilatation – its role in the therapy of anal fissures. Dis Colon Rectum 1992; 35 (4): 322-327. 29. Renzi A: Clinical, manometric and ultrasonographic results of pneumatic balloon dilatation vs. lateral internal sphincterotomy for chronic anal fissure: a prospective, randomized controlled trial. Dis Colon Rectum 2008; 51(1): 121-7. 30. Keighley MBR et al.: Treatment of anal fissure by lateral subcutaneous sphincterotomy should be under general anaesthesia. Brit J Surg 1992; 68: 400-401. 31. Littlejohn DRG, Newstead GL: tailored lateral sphincterotomy for anal fissure. Dis Colon Rectum 1997; 40, 12: 1439-1442. 32. Yuksel O: Keyhole deformity: a case series. Journal of Gastrointestinal Surgery 2008; 12(6): 1110-4.

otrzymano/received: 2009-09-12
zaakceptowano/accepted: 2009-09-17

*Agnieszka Kucharczyk
Szpital na Solcu w Warszawie
ul. Solec 93, 00-382 Warszawa
tel.: (0-22) 625-22-31

The whole paper current views on etiopathogenesis and treatment of anal fissures is also available at On-line Medical Library.
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